[1] Jumbo made her Broadway debut in Jez Butterworth's The River in 2014, and received her second Olivier nomination upon her 2021 return to the London stage as Hamlet.

[7] She has also appeared in productions of The Cherry Orchard, The Crucible, The Caucasian Chalk Circle, Richard III[8] and Pygmalion at the Royal Exchange Theatre in Manchester for which she received MEN and Ian Charleson Award nominations.

In 2012 she won the Ian Charleson Award for her performance as Rosalind in William Shakespeare's As You Like It at the Royal Exchange Theatre, Manchester.

Jumbo played Constance Neville in She Stoops to Conquer at the National Theatre in 2012 and Mark Antony in an all female production of Julius Caesar at the Donmar Warehouse for which she received a nomination for an Olivier Award.

She made her Broadway debut in the autumn of 2014 when she appeared in the transfer of the Royal Court Theatre production of The River by Jez Butterworth, alongside Laura Donnelly and Hugh Jackman.

[15] Jumbo also co-wrote the musical Rebels and Retail, a shortlisted entrant in the Perfect Pitch West End Showcase 2008.

On television, Jumbo has appeared in My Family, Harley Street, as receptionist Hannah Fellows, as Lois Habiba in all five episodes of Torchwood: Children of Earth, as Becky on BBC Three's drama series Lip Service, Casualty and as Nurse Damaris in Getting On Series 2 and 3, written by Jo Brand, Jo Scanlon and Vicki Pepperdine in which Jumbo was directed by fellow Torchwood actor Peter Capaldi.

[17] In October 2021, Jumbo played the title role in a production of Hamlet at the Young Vic Theatre in London, directed by Greg Hersof.