The men's time trial class C4-5 track cycling event at the 2020 Summer Paralympics took place on 26 August 2021 at the Izu Velodrome, Japan.

This combine class (C4-5) under classification C is for cyclists who have impairments that affect their legs, arms, and/or trunk but are still capable to use a standard bicycle.

21 cyclists from 15 nations competed in this event.

[1] The competition immediately starts off with the finals, where all 21 cyclists will be divided into their own heat individually (so 1 heat contains 1 cyclist).

Cyclists in class C4 can have a lesser-official time than their real-time due to the athletes factor where in class C4 the factor is 98.91% while C5 is 100.00%, so the time cyclist in class C5 get, will be their official time.