She was a member of the House of Representatives for the Lone District of Las Piñas from 2001 to 2010 before winning a seat in the Senate in 2013, placing tenth.

Villar was born on July 29, 1950, in Muntinlupa, then a municipality in Rizal, to Filemon Aguilar, a long-time mayor of Las Piñas and congressman, and Lydia Ampaya.

[2] She practiced as a financial analyst at the Philippine Shares Corporation and a professor at the Far Eastern University before marrying Villar in 1975.

After her marriage, she helped her husband in managing his business ventures and became the director and vice president of the Household Finance Corporation.

When Manny Villar became Speaker of the House of Representatives in 1998, she became the chairwoman of the Congressional Spouses Foundation, serving until 2000.

In the year of 2001, Villar ran as Representative of the Lone District of Las Piñas and won in a landslide victory.

[3][5] In 2013, Villar ran as senator under the ticket of his husband's rival in the 2010 presidential elections, President Benigno Aquino III and won, finishing in 10th place.

[7] On July 10, 2014, Villar criticized the arrest of senators Bong Revilla, Juan Ponce Enrile, and Jinggoy Estrada after the three were linked as the masterminds to the Priority Development Assistance Fund scam or Pork Barrel scandal.

[11] In October 2016, Villar backed President Duterte's Philippine Drug War,[12] which according to rights groups and activists has killed at least 20,000 Filipinos.

[13] In November 2016, Villar voted against a resolution which sought to reject the Duterte-initiated burial of the late dictator Ferdinand Marcos in the Libingan ng mga Bayani.

[14] In February 2017, Villar voted in favor of the Tax Reform for Acceleration and Inclusion Act,[14] which increased the inflation rate and cost of goods in the country.

[17] On December 13, 2017, Villar was unable to vote for the martial law extension in Mindanao, but senator Vicente Sotto III noted that she “would have voted yes.”[14] On March 6, 2018, Villar stated that she has 'no conflict of interest' into investigations into the status of Boracay, despite her family's ownership of properties on the island.

[20] On May 17, 2018, Villar did not support the resolution against the ouster of Chief Justice Maria Lourdes Sereno via a quo warranto petition.

[24] In a senatorial forum on GMA News TV on February 23, 2013, economist Winnie Monsod asked Villar to explain why, as chairman of the House Committee on High Education, she opposed the move to close nursing schools that the Commission on Higher Education (CHED) said did not meet minimum requirements to continue operations.

Ako, matalino akong tao, pero hindi ko maintindihan yung research niyo.

)"[26] Criticisms for this statement came from multiple sources, including news articles[27][28] and comments on recorded footage of Villar saying it.