Cyprus sent a delegation to compete at the 2016 Summer Paralympics in Rio de Janeiro, Brazil, from 7 to 18 September 2016.

The Cypriot delegation to Rio de Janeiro consisted of two athletes: sprinter Antonis Aresti and short-distance swimmer Karolina Pelendritou.

[1] At the close of the Rio Games, the nation had won a total of six medals in their history in the Paralympic movement.

[2] Two athletes were sent by Cyprus to Rio de Janeiro: sprinter Antonis Aresti and short-distance swimmer Karolina Pelendritou.

This led Aresti to take up sprinting and made his international debut at the 2006 Dutch World Track and Field Championship.

[10][11][12] Aresti stated to the Cyprus News Agency that his goal was to reach the final of his event and then win another Paralympic medal.

[14][15] Born on 25 August 1986,[16] Karolina Pelendritou has lost 97 per cent of her central vision in her retina, rendering her unable to see details from a long distance.