The Ministry of Foreign Affairs of the Czech Republic (MFACR; Czech: Ministerstvo zahraničních věcí České republiky; MZVČR) is a Czech government ministry responsible for international relations of the Czech Republic.

The Ministry is headquartered in Černín Palace, Loretánské náměstí 5, 118, Prague 1,[1] (Hradčany).

The Ministry operates the diplomatic missions of the Czech Republic abroad and is responsible for implementing the foreign policy of the Czech Republic and Czech diplomacy efforts.

The Ministry is led by the Minister of Foreign Affairs, who is nominated by the Prime Minister of the Czech Republic.

The current Minister of Foreign Affairs is Jan Lipavský, in office since 17 December 2021.