The orchestra principally gives concerts at the Smetana Hall, Municipal House (Smetanova síň Obecního domu).

In March 2019, the CNSO announced the appointment of Steven Mercurio as its next chief conductor, effective with the 2019–2020 season.

[1] In popular music collaborations, the orchestra played on the Ulf Lundell album På andra sidan drömmarna in 1996.

Lotta Engberg recorded Nära livets mening together with the orchestra in 2003, and the song was included on the 2005 album Kvinna & man.

In July 2015, Morricone conducted the orchestra for recording sessions of his film score to Quentin Tarantino's The Hateful Eight.