Débora was born in Belo Horizonte City, the daughter of actor Rogério Falabella and the lyrical singer Maria Olympia.

In a casting for actors, Falabella got her entrance into the most famous Brazilian television network, Rede Globo, in one of the seasons of the young adult series Malhação in 1998.

Falabella also began starring in films such as Françoise, for which she was awarded Best Actress at the Festivals of Gramado and Brasilia, and received an honorable mention at the BR River Festival 2001; Dois Perdidos numa Noite Suja,[3] a 2002 film directed by José Joffily, for which she won awards for best actress in Brazil and a cinema Candango trophy; 2003 Lisbela e o Prisioneiro,[4] and in 2004 Cazuza with Daniel de Oliveira.

[8] In 2011, she played Clarisse, one of the main characters in the Emmy winner series, The Invisible Woman, and starred again with actor Rodrigo Santoro, in the films My Country[9] and Homens do Bem.

[10] In 2012, Falabella returned to telenovelas, starring in the most successful television production, Avenida Brasil receiving several nominations for Best Lead Actress.