Any Department of State officer or other official under the authority of the chief of mission can make a démarche.
Unless the Department of State provides specific instructions as to rank (for example: "the Ambassador should call on the Foreign Minister"), the embassy has discretion to determine who should make the presentation and which officials in the host government should receive it.
After delivering the démarche, the embassy should report to the Department of State via front-channel cable.
It should provide the name and title of the person to whom the démarche was made, and record that official's response to the presentation.
As appropriate, the reporting cable should also describe any specific follow-up action needed by the embassy, Department of State, or the foreign government.