Désiré Defauw (5 September 1885, Ghent, Belgium – 25 July 1960, Gary, Indiana, United States) was a Belgian conductor and violinist.

Defauw was a pupil of the violinist Johan Smit (1862-1932) and gave his first London performances in 1910.

During World War I he became a refugee working in London, founding the Allied Quartet with Charles Woodhouse (second violin), Lionel Tertis and Emile Doehaerd.

[2] The same year he also appeared at the Wigmore Hall performing John Ireland's Violin Sonata No.

[3] He was professor of conducting at the Brussels Conservatory and was the first conductor of the Orchestre National de Belgique from 1937.