DF Malan is also notable for producing several famous musicians on the local South African music scene, such as Pierre Greeff and Hunter Kennedy.

Consequently, many local bands including aKing, Foto na Dans, Jax Panik, Lukraaketaar, Die Heuwels Fantasties and Frik13 are associated with the school.

[2] Also on the music scene DF Malan produced musician Loki Rothman, who reached the final of SA's Got Talent in 2009 (while still a senior in the school), and the founding members of Cape Town alt-pop duo EMERGER: Emma de Goede and Gerrit "Gerry" Matthee.

[3] Their debut single "Break & Fall" was a winner of the international Avid and Abbey Road Studios Song Contest and they were featured as Apple Music's New Artist Spotlight in July 2018.

[4] Other notable alumni include former Springbok rugby player Werner Greeff, international cricket umpire Marais Erasmus, ballet dancer Eduard Greyling and a former dean of Engineering at the University of Stellenbosch, Prof Arnold Schoonwinkel.