Don Samuel Goonesekera (13 November 1896 – 7 August 1983) was a politician and member of parliament.

Don Samuel Goonesekera was born 13 November 1896 in Habaraduwa, the only son of Don Marthelis Goonesekera and Dona Clare Abeygoonewardena.

At the first parliament election in 1947 he contested the seat for the Udugama Electoral District, on behalf of the United National Party, becoming its first MP.

In the subsequent parliamentary election in 1952 he lost the seat, after switching to the Sri Lanka Freedom Party.

Their daughter, Damithri, also became a consultant eye surgeon; Sanath, a medical administrator; Vineetha Indrani and Mahinda, medical specialists; and Palitha, an attorney at law.