Established in 2005, the DCU Saints initially competed in the Irish American Football League (IAFL) for five seasons, reaching the playoffs in 2008 and 2009.

The club initially provided flag football training and access to some of the NFL games.

[citation needed] Also in 2006, a cheerleading squad was formed with the assistance of DCU Dance.

[citation needed] Between 2006 and 2010, the club played in several IAFL competitions, before disbanding.

[citation needed] However, the club disbanded prior to the start of that season.