They also researched, developed and marketed the first ever forensic genomics product - DNAWITNESS - which was used to create a physical profile of donors of crime scene DNA.

[3] DNAPrint's most controversial offering was "DNAWitness", a product that uses the same Ancestry Informative Markers for a forensic purpose, as well as polymorphisms in the human OCA2 gene and others to make inference about iris (eye), hair and skin color.

DNAPrint was the first to research and publish the linkages between OCA2 polymorphisms and human eye color and by integrating these with the same ancestry informative markers used with its consumer BGA tests for analysis with DNA evidence from crime scenes, DNAPrint Genomics was able to help narrow down suspects based on the construction of an "in-silco constructed, database driven" physical trait or phenotype profile.

[10] It is rare that a DNA chunk is conserved in two individuals from a common ancestor who lived more than ten generations (around 300 years) in the past.

[10] Finally, each company uses unique algorithms to make the time estimates and the approximate amount of relatedness of the DNA donor to their ancestors.

Aside from the percentage problem, genetic testing processes such as AncestrybyDNA—especially in the context of uncovering a racial background—is connected to the perpetuation of the myth of race.

As stated by the National Human Genome Research Institute, "Race is a fluid concept used to group people according to various factors including, ancestral background and social identity.

[14] In the early 2000s, under the leadership of founder and then CEO Tony N. Frudakis, Ph.D., DNAPrint forged a nascent consumer genetics/genomics and forensic phenotyping marketplace.

In the mid to late 2000s many journalists and academics harshly criticized DNAPrint's application of genomics research for consumer and forensic purposes but by the early 2000-teens, the forensic science applications of BioGeographical Ancestry (BGA) admixture analysis for the inference of BGA and certain anthropometric phenotypes such as skin shade, eye/hair color, had become well established and by 2019 the market for these types of products had grown to over $500M/year in size.

Applied Biosystems) and next generation sequencing platform and consumable manufacturers have introduced human identity products combining classical (CODIS eligible) STR profiling marker sets with unique SNP based AIMS for the inference of BGA and phenotype (e.g. ForenSeq, from Illumina's Verogen).

In the mid-2000s, Frudakis wrote the seminal textbook introducing the forensic and consumer market application of genome-derived marker panels.

For example, in forensics, over 70 serial homicide cases (including the Golden State Killer) having been solved through genetic genealogy hits enabled by the types of consumer genomics databases DNAPrint was the first to introduce.