The major conductors who worked with the orchestra during this period, from 1976 to 1982, were Erich Leinsdorf, Eugen Jochum, Gerd Albrecht, Gennady Rozhdestvensky and Neville Marriner.

However, after reports of disputes over financing and a threatened reduction in the size of the orchestra, in March 2009, Metzmacher announced his early resignation from the DSO-Berlin principal conductorship as of the summer of 2010.

[4] In September 2010, the DSO-Berlin announced the appointment of Tugan Sokhiev as its Principal Conductor and Artistic Director, as of 2012, with a contract of 4 years.

[9] In March 2023, a news report indicated that Ticciati is to stand down as principal conductor of the orchestra in 2025,[10] two years ahead of his previously announced contract extension.

[12][13][14][15] In 2011, the orchestra won a Grammy Award for its recording of Kaija Saariaho's L'amour de loin, conducted by Kent Nagano.