[2] In 1981, Daddy-O began his career as the lead member of the band Stetsasonic, which included Prince Paul, in Brooklyn, New York.

He produced and remixed songs for musical acts such as Mary J. Blige, Queen Latifah, Red Hot Chili Peppers, The B-52's, Jeffrey Osborne, Chante Moore, and Lil' Kim.

After leaving MCA, he worked for Motown Records and various other entertainment agencies, where he helped to produce and discover talent.

Other acts with which he has been associated include Sonic Youth, Sublime, Barry White, They Might Be Giants, Camron, Pizzicato 5, and Third World.

[5] In 2016, Daddy-O and his partner Lion Lindwedel (founder of True School Entertainment) formed their co-owned label, Odad Truth Records.