The station is located on CSX's S-Line, which runs along the east side of the building.

Built in 1912 by the Atlantic Coast Line Railroad (now CSX Transportation), it is located on the U.S. 98/301 Bypass, across the street from East Meridian Avenue (SR 52).

Finally, in 1990, Amtrak brought passenger service back to Dade City by rerouting the Silver Star over the S-Line through Ocala and Wildwood, FL to Miami.

[6][7] Two years later, the Palmetto was truncated to Savannah, Georgia on November 1, 2004, prompting Amtrak to revive Silver Star service to Tampa along the CSX A-Line shared by the current Silver Meteor, and part of the suspended Sunset Limited, and ending passenger service to Dade City once again.

The station was preserved and reopened as a tourist destination with a grand re-opening held on October 23, 2008.