He is best known as the creator, director, co-writer and executive producer of The Chosen, the first multi-season series about the life of Jesus of Nazareth.

However, Jenkins' mind was changed when he was mowing his lawn—he estimates in 2006 or 2007—and he felt that God was telling him to make Christian film content.

[6][5] After producing Hometown Legend and directing two short films, Jenkins' feature-length directorial debut was Midnight Clear in 2006.

The film, which starred Stephen Baldwin and was distributed by Lionsgate, was based on a short story written by his father, Jerry Jenkins.

[17] The film got the attention of the filtering and streaming service VidAngel, which was embroiled in a copyright infringement lawsuit with major Hollywood studios and thus seeking original content to distribute.

VidAngel suggested putting the short film on Facebook as a concept pilot to generate interest for Jenkins' idea of a multi-season series.

The ministry has produced four films: The Ride in 2012,[20] Once We Were Slaves (retitled The Two Thieves) in 2014,[21] The Resurrection of Gavin Stone in 2017,[22] and The Shepherd in 2017.

[24] The Chosen is a 2017 television drama based on the life of Jesus Christ, created, directed and co-written by Jenkins.

[29][30][31] Jenkins owns a stake in the company but won't share profits until the startup investors earn back their initial investment plus 20 percent.

[28] In April 2022, Jenkins apologized to fans for not informing them about a gag marketing campaign involving defacing their own billboards promoting The Chosen.

"[4] Jenkins announced that he will be directing a feature-length film adaptation of the book The Best Christmas Pageant Ever, to be released late 2024.