He graduated in literature at the Ca' Foscari University of Venice, and directing at the Scuola d'Arte Drammatica Paolo Grassi in Milan.
[1] He staged some rarely performed operas by Ramón Carnicer, Michael Daugherty, Nino Rota, Stefano Pavesi and Marco Tutino.
At the Salzburg Festival, he directed again Verdi's Falstaff, Rossini's La Cenerentola, with Cecilia Bartoli in the title role.
[1] Michieletto directed Massenet's Cendrillon at the Komische Oper Berlin in 2016 and the world premiere of Filippo Perocco's Aquagranda [de] at La Fenice in 2016, written on a commission on the occasion of the 50th anniversary of the 1966 acqua alta flooding.
In 2021 Michieletto makes his debut at Berlin State Opera with Jenufa conducted by Simon Rattle and comes back to La Scala Milan with Salome by Strauss.