She was known for playing Audrey Griswold in National Lampoon's European Vacation, and also known for her roles in Shoot the Moon and Cross Creek.

Hill had type one diabetes that affected physical growth, which meant that she often played children into adolescence and beyond.

Her first job was a 1973 commercial for the YMCA, spinning a basketball on her finger with Boston Celtics center Dave Cowens.

The same year, she played Frankie Addams, the lead character in the made-for-TV adaptation of The Member of the Wedding, co-starring with Pearl Bailey.

She starred with Rip Torn and Mary Steenburgen in the 1983 film Cross Creek, a semi-biographical story about Marjorie Kinnan Rawlings, author of The Yearling.

The same year, she appeared in Shelley Duvall's 1980s children's TV series Faerie Tale Theatre, playing the princess in an episode titled "The Boy Who Left Home to Find Out About the Shivers".

The producers of the 1983 movie National Lampoon's Vacation were planning a sequel, but Anthony Michael Hall declined to reprise his role as son Rusty Griswold, choosing instead to do the film Weird Science.

The producers decided to recast the roles of both Griswold children, and so for National Lampoon's European Vacation, Hill was chosen to replace Dana Barron, the original actress who portrayed Audrey.