Daniel Giménez Cacho was born on May 15, 1961 in Madrid,[1] as the youngest of the six children of Luis Giménez Cacho and Julia García Casado [es], two actors who performed in the theatre company La Barraca.

[3] He starred in several Mexican films and television series, such as Sólo Con Tu Pareja, Cronos, Midaq Alley, Tear This Heart Out and Bad Education.

He has worked with several prominent Hispanic filmmakers, including Guillermo del Toro, Alfonso Cuarón, Jorge Fons and Pedro Almodóvar.

He appeared in La hora marcada, the series written and directed by Alfonso Cuarón and Guillermo del Toro, and in the Mexican telenovela Teresa.

[5][6] In October 2023, he joined the open letter called "Artists Against Apartheid" during the concurrent escalation of violence in Palestine.