Daniel Ionuț Isăilă (born 29 June 1972) is a Romanian professional football manager and former player.

In August 2012, he moved to second division club FCM Târgu Mureș, where he received a contract for a season with the main objective being promotion in Liga I.

After the best performance of Astra Giurgiu in the Championship, (2nd place) he qualified his team in the Europa League group stages for the first time, winning against Lyon in a fantastic double match which will remain in the history of the club.

In October the same year, he became one of the assistant coaches for the Romania national team working under Anghel Iordănescu and later Christoph Daum.

After nearly two years in control he gave up the national team, thus leaving it with chances of qualifying to the 2019 UEFA European Under-21 Championship.