Isaac produced and starred in what became a television pilot, According to My Mother, with Cathy Yan and Devin Landin.
[1] The role was initially written to be to a three-episode part, but the writers ended up making the character a series regular the first two seasons.
Isaac also stars as a bike courier with a foot fetish in the BDSM-focused web series Mercy Mistress, produced by Margaret Cho.
[8] He also played the role of "Sandwich Artist" in the May 22, 2022 Episode (#251) of the HBO series Last Week Tonight with John Oliver.
[9] Also in 2022, it was announced that Isaac would star in the comedy film Plan B, alongside Jon Heder, Tom Berenger, and Shannon Elizabeth.