1985 he obtained his PhD in physics in Zurich with a thesis on statistical mechanics under the supervision of A. Thellung.

After postdoctoral stays in Zurich and at the University of Illinois in Urbana, where he worked with Anthony Leggett, he worked as a research scientist at the IBM T. J. Watson Research Center in Yorktown Heights.

Loss' research concerns the quantum theory of condensed-matter- and solid-state physics.

He is one of the leading theorists investigating the realization of quantum information processing protocols in semiconductor structures.

[5] Further lines of research include decoherence, nuclear spin physics, topological matter, Majorana fermions and parafermions.