He started acting as a child at the age of nine when he auditioned for the Royal Shakespeare Company and was selected out of hundreds of other children.

Sharman initially had difficulty transition to acting on film, as he found it "odd and unnatural", but he eventually adjusted.

Beginning in 2012, Sharman had a major recurring role as werewolf Isaac Lahey in MTV's supernatural drama series Teen Wolf.

In the following year, Sharman narrated the audiobook version of Cassandra Clare's young adult novel Clockwork Princess, the third and final installment of her Infernal Devices trilogy.

[9] In March 2014, after the season 3 finale, it was announced that Sharman would be leaving Teen Wolf as he wanted to explore other opportunities.

In March 2019, Sharman joined Cursed, a Netflix television series based on a re-imagining of the Arthurian legend.