[5] Bermúdez made her professional debut on 26 March 2010, scoring a four-round split decision (SD) victory over Roxana Virginia Baron at the Estadio Pedro Estremador in Bariloche, Argentina.
[13] A month later she made her first attempt at a world title by challenging reigning WBA light-flyweight champion Yésica Bopp on 24 September at the Polideportivo Posta del Retamo in Junín, Argentina.
[15] Following a second-round technical knockout (TKO) win over Marta Soledad Juncos in January 2012,[16] she faced Mayerlin Rivas on 31 March at Club Atlético Talleres in Villa Gonernador Gálvez, Argentina, with the vacant WBA interim bantamweight title on the line.
[18] She fought another two times in 2012; a successful defence of her interim super-flyweight title via second-round technical knockout against Olga Julio in August[19] and a unanimous decision victory over Anahi Yolanda Salles in a six-round non-title bout in December.
[26] Following the loss to Bopp, Bermùdez moved back up to super-flyweight to successfully defend her WBO title against Vanesa Lorena Taborda in January 2015, winning by majority decision.
[33] Six months later, Bermúdez moved up in weight yet again, challenging reigning IBF junior-featherweight champion Marcela Acuña on 13 April 2018 at the Microestadio Municipal in Buenos Aires.
[36] On 4 December 2020, Bermúdez claimed the vacant IBF female junior-featherweight title by stopping Cintia Gisela Castillo in the 10th round of their contest in Zavalla, Argentina.
[37] [38] Switching weight divisions again for her next fight on 25 March 2021, Bermúdez challenged WBC and WBO female featherweight champion Amanda Serrano in a bout that was also for the vacant IBO crown.