Over his career, which spanned three decades, Orsato refereed a UEFA Champions League final and received accolades from the International Federation of Football History & Statistics.

On 12 February 2019, Orsato refereed the UEFA Champions League round of 16 first-leg match between Manchester United and Paris Saint-Germain.

[9] On 20 November 2022, Orsato was appointed as the referee for the opening match of the 2022 FIFA World Cup between hosts Qatar and Ecuador.

[11] On 7 May 2024, Orsato refereed the second leg of the 2024 UEFA Champions League semi-final between Paris Saint-Germain and Borussia Dortmund where he earned praise for his performance on the night, especially his decision to award PSG a free-kick at the edge of the box when a penalty appeared to be the correct call.

In the summer of 2024, Orsato was included in the expert referee commission of the Russian Football Union, but a week later he refused this job.