Daphne van de Zande (born 21 July 1974 in Vilvoorde) is a Belgian former tennis player.

She has career-high WTA rankings of 161 in singles, achieved on 22 June 1998, and 210 in doubles, reached on 5 October 1998.

Van de Zande won four singles and three doubles titles on the ITF Circuit in her career.

She made her WTA Tour main-draw debut at the 1997 Pattaya Open.

Van de Zande retired from professional tennis 2011.