[9] Parts of the song can be heard from Aoki's performance on February 28, 2015 at the Aragon Ballroom in Chicago, Illinois.

Dance Charts, a German dance music website, gave the song a positive response and claiming that the song would chart higher than their previous collaboration, saying that "the mixing of the various elements are pretty good at "Darker Than Blood".

"[13] In a more mixed review, Direct Lyrics criticized the song saying, "It’s a shame that all of Chester’s intensity gets overclouded by Steve Aoki's commercial EDM beat.

[18] The video takes place in the year 2052 in the midst of a zombie apocalypse, where a virus has infected almost the entire world population.

Shinoda and Aoki play scientists who work at the Centers for Disease Control and Prevention, who are trying to create a serum that will hopefully cure the infection.

So far they are unsuccessful, as the experimental serums they are testing on patients (who are actually asymptomatic carriers of the virus) shows no effect.

Intercut with these scenes also depicts a young boy (whose name is revealed to be Steven A. and have the same tattoo on the same place like Aoki towards the end of the video) who is trying to search for the center guided by a crudely drawn map, while being chased by several zombies.

As the scientists, Shinoda, and Aoki celebrate their success, a graphics screen is displayed, showing that the number of cured survivors is rising at an incredibly fast rate.