Nearby localities include al-Janudiyah, Zarzur and al-Najiyah to the southwest, Jisr al-Shughur to the south and Millis and Maarrat Misrin to the east.

[8] In the early 1960s it was described a large village of 2,500 residents and "one of the most picturesque" places in the area by geographer and author Robert Boulanger.

[2] During the ongoing Syrian civil war which started in March 2011, Darkush was captured by anti-government forces in November 2012.

By late January 2013, the town was firmly in rebel hands and is used as a launching point for military operations against government-held positions in the mountains to the south.

[10] The town of Darkush lies in a wadi in the Orontes River basin, at the foothills of the an-Nusayriyah Mountains.