Darleane Christian Hoffman (born November 8, 1926) is an American nuclear chemist who was among the researchers who confirmed the existence of seaborgium, element 106.

[3] Her father was a mathematics teacher and superintendent of schools; her mother wrote and directed plays.

[8] She left Los Alamos in 1984 to accept appointments as tenured professor in the department of chemistry at UC Berkeley and Leader of the Heavy Element Nuclear & Radiochemistry Group at Lawrence Berkeley National Laboratory.

[9] Over her career, Hoffman studied the chemical and nuclear properties of transuranium elements and confirmed the existence of seaborgium.

[10] Right after finishing her doctoral work, Darleane Christian married Marvin M. Hoffman, a physicist.