He is the Edgerly Professor and chairman of the department of Neurology at the Yale School of Medicine, where he works on immunity, genetics, and multiple sclerosis.

The Company's products, which induce tissue-specific immunosuppression without toxicity, are based upon the principles of oral tolerance.

[2] In 2009, Hafler and his laboratory moved to Yale Medical School in New Haven, Connecticut, where he became the Glaser Professor and chairman of the department of Neurology.

It was awarded "for fundamental discoveries related to MS in fields such as immunology and genetics, and for bringing clinical importance to basic science findings.

This endowed professorship was provided by William S. and Lois Stiles Edgerly who had long supported research in multiple sclerosis.