David Bailey (pharmacologist)

David George Bailey (March 17, 1945 – August 27, 2022) was a Canadian track and field athlete, and subsequently a recognized pharmacologist, who pioneered the research of grapefruit–drug interactions.

He was a member of 9 Canadian national track and field teams, competing at: Bailey completed undergraduate studies in Pharmacy (1968) and graduate work in Pharmacology (M.Sc.

Clinically, the concern is that a single judicious amount of grapefruit ingested even many hours beforehand would noticeably boost oral drug bioavailability and cause overdose toxicity.

Formal product information for a number of highly prescribed or essential medications now warn about the risk of a grapefruit-induced adverse drug interaction.

[6] A review article of his on the topic of grapefruit–drug interactions was republished in a special 2004 Anniversary Edition of the British Journal of Clinical Pharmacology, which reprinted only 14 publications that were considered of major importance over the past 30 years.

In later years, Bailey shifted the focus of his research slightly to assessing the effect of fruit juices on other potentially important mechanisms of drug absorption.