His parents were Zionists and in 1924 they immigrated with three children (Nora, David and Ida) and settled in the Jaffa section of Tel Aviv.
Immediately after graduation from high school, David Danon joined the Irgun (Etzel) and his nom de guerre was "Ehud".
[2][3] He joined the Irgun together with his two classmates and close boyhood friends Amichai Paglin (who was later to become the Chief Operations Officer of the Irgun, Prime Minister Menachem Begin's counter-terrorism advisor, and Prime Minister Begin's Ambassador to the United States) and Eliyahu Bet-Zuri (who later joined the more militant Lehi, and was executed in Egypt for the assassination of Lord Moyne).
Per agreement with the British, David traveled to Geneva by ship within one or two days of his release from Latrun and began his medical studies.
Having collected the needed arms, he prepared to send them from France to the Irgun on the ill-fated ship, the "Altalena", which departed for the newly created state of Israel, then in the midst of its War of Independence.
Thus, David Danon developed the Microtome (a device for cutting extremely thin slices of tissue) for use on the electron microscope.
His pearly research in the Institute's Electron Microscopy Laboratory involved the membrane structure of erythrocytes, their adherence and thrombocytes.
[10] In 1957, while working at the Weizmann Institute David Danon founded with Dr. Kalman the Department of Physiology and Anatomy of Animals, at the Faculty of Agriculture in Rehovot where he taught until 1962.
At this time he developed and built Fragiligraph, – a device that enables automatic registration of osmotic fragility curve of erythrocytes, later produced by "Elron".
[13] During a Sabbatical in geriatric medicine at Montefiore Hospital in New York in 1984-1985, he devoted major efforts to alleviating the suffering of patients with pressure ulcers.
From 1993 onwards Prof. Danon devoted himself entirely to the development of a unique, remarkably simple, yet new method for the treatment of severe wounds, based on the injection of "activated" macrophages.
Macrophages were prepared from a blood unit in a closed sterile system that consisted of a number of interconnected plastic bags.
However, after consultation on this issue with his colleagues at the Weizmann Institute, especially president Ephraim Katzir, Prof Danon came to the conclusion that it was preferable for him to continue to engage in scientific research.
In 2011 David Danon had a solo exhibition at the "Foyer gallery" in Petah Tikva, by the name "Seventy Years of Painting".