David Ezra Green (August 5, 1910 – July 8, 1983) was an American biochemist who made significant contributions to the study of enzymes, particularly the electron transport chain and oxidative phosphorylation.

He then moved to England and worked for eight years at the University of Cambridge under the supervision of Malcolm Dixon, on redox reactions in biological systems.

He received his PhD under Dixon in 1934 with a thesis entitled The Application of Oxidation-Reduction Potentials to Biological Systems.

At the outbreak of the Second World War, Green moved back to America and established himself in a laboratory at Columbia University.

He is the father of biochemist Rowena Green Matthews and grandfather of Wisconsin Senator Tammy Baldwin.