Actors including Al Pacino, Robert De Niro, Dustin Hoffman, Robert Duvall, Jon Voight, Stockard Channing, James Woods, Blythe Danner, Larry Bryggman, John Cazale, Hector Elizondo, Spalding Gray, Paul Guilfoyle, Ralph Waite and Paul Benedict were part of the company.
While the Charles produced well-known classics by authors such as Tennessee Williams and Arthur Miller, TCB produced adventurous new works by controversial playwrights such as Harold Pinter, Samuel Beckett, Sam Shepard, Edward Albee, Bertolt Brecht, Ed Bullins, Jeffrey Bush, John Hawkes, and Adrienne Kennedy.
[11] Wheeler cast his plays out of Boston and New York, helping to launch the careers of then unknown young actors including Paul Benedict, Hannah Brandon, Larry Bryggman, John Cazale, Stockard Channing, Blythe Danner, Robert De Niro, Robert Duvall, Hector Elizondo, Spalding Gray, Paul Guilfoyle, Dustin Hoffman, Al Pacino, Jon Voight, Ralph Waite, and James Woods.
in Cambridge, Massachusetts as Resident Director in 1984, where he directed over 20 productions, including Harold Pinter's The Homecoming and The Caretaker; George Bernard Shaw's Man and Superman, Heartbreak House, Misalliance, and The Doctor's Dilemma; Don DeLillo's Valparaiso (world premiere, with Will Patton) and The Day Room; Othello, How I Learned to Drive starring Debra Winger and Arliss Howard, Nobody Dies on Friday, Waiting For Godot (1995), Picasso at the Lapin Agile, What the Butler Saw, True West, Angel City, Cannibal Masque, Gillette, Two by Korder: Fun and Nobody, and David Mamet's adaptation of Chekhov's Uncle Vanya (with Christopher Walken as Astrov and Lindsay Crouse).
[11] At Trinity Repertory Company, Wheeler directed seventeen productions (from 1982–1993), including the world premiere of Tom Griffin's The Boys Next Door (later remounted at the A.R.T.