David Keller Leighton, Sr. (January 22, 1922 – August 7, 2013) was the American bishop of the Episcopal Diocese of Maryland 1972–1985.
He served in the United States Army Air Forces during World War II.
In 1947, Leighton graduated from Northwestern University and worked for General Motors.
Between 1959 and 1963, he served as rector of the Church of the Holy Nativity in Forest Park, Baltimore.
He subsequently was a teacher of sacred studies at the St. Paul's School (Brooklandville, Maryland).