David Meriwether (October 30, 1800 – April 4, 1893) was a United States Senator from Kentucky and a Governor of the New Mexico Territory.

He attended the common schools and engaged in fur trading in 1818 near what is now Council Bluffs, Iowa.

Meriwether was appointed as a Democrat to the United States Senate to fill the vacancy caused by the death of Henry Clay, and served from July 6, 1852, to August 31, 1852, when Archibald Dixon was elected his successor.

In 1853, Meriwether was appointed by President Franklin Pierce as Governor of the Territory of New Mexico[1] after the position was turned down by Solon Borland, and continued in office to 1855.

From April to July 1854, when Meriwether was out of state, the Secretary of the Territory, William S. Messervy, was acting Governor.