He is the official Italian voice-over artist of Elijah Wood and Jesse Eisenberg.

[1] Perino is mainly active in the voice acting and dubbing industry where, apart from voicing a few Italian animated characters, he has notably dubbed Wood's live action role of Frodo Baggins in The Lord of the Rings trilogy and the majority of the American actor's remaining film roles, Cody Kasch in the role of Zach Young on Desperate Housewives, Kristopher Turner as Jamie Andrews in the series Instant Star, Colin Morgan in Merlin, Ryan Corr in the second season of Blue Water High, where he played Eric Tanner, Aaron Ashmore as Jimmy Olsen in Smallville and Chace Crawford in the role of Nate Archibald in Gossip Girl.

He also lent his voice to Lucas Grabeel in the role of Ryan Evans in all the High School Musical films as well as Zachary Garred in the show Foreign Exchange.

In animation, Perino has dubbed Sasori in Naruto Shippuden, Harry Osborne in Spectacular Spider-Man, Cody in the Total Drama series and also the Looney Tunes characters Sylvester the Cat and Wile E. Coyote.

In films, he also dubbed Walter in The Muppets and Sam Witwicky in the live-action Transformers trilogy.