[6][7] Born in Viareggio in Tuscany, he attended the Harry Hopman academy in Florida and then UCLA.

In 1998, Sanguinetti made a run to the Wimbledon quarter-finals, defeating Johan Van Herck, Franco Squillari, Vladimir Voltchkov and Francisco Clavet before losing to Richard Krajicek in straight sets.

He defeated Carlos Moyá and Paradorn Srichaphan – the latter in a four-and-a-half-hour match – before losing to David Nalbandian.

However, he gained a bit of redemption when he upset Nalbandian in the first round of the Rogers Cup in Toronto on 7 August 2006.

Sanguinetti has a .500 record in Davis Cup matches, last playing against Zimbabwe in 2003, defeating Nigel Badza and losing to Wayne Black.