The School of Business was founded in 1952 but was renamed in 1992 in honour of successful Canadian entrepreneur and philanthropist Michael G. DeGroote.

To enter into the honours program, students must have completed all required courses with no failures and have a cumulative average of at least 5.0.

Partners for the internship program include Procter & Gamble, RBC, CIBC, CPPIB, Dofasco, Manulife, Deloitte, IBM, Microsoft, Ford and others.

A typical graduating class consists of 30% Finance, 30% Health, and 25% Marketing majors; the school also offers Accounting, Strategic Business Valuation, eBusiness, Innovation & New Technology, Operations Management, Information Systems and Human Resources streams.

The school also houses the Allen H. Gould Trading Floor, an educational tool that enables students to experience the relationships and interactions of the financial markets.