The next year, Stephen Moulton Babcock and Elmer McCollum began the single-grain experiment, which fostered the development of agricultural chemistry at Wisconsin.

The experiment continued in the Agricultural Chemistry Building when it was built in 1912 and was expended to identify the key elements in nutrition.

Steenbock made his most significant discovery in 1923, when he established a relationship between vitamin D and ultra-violet light on bone health.

[2] Conrad Elvehjem isolated nicotinic acid (niacin) at the Agricultural Chemistry Building in 1937, which cured pellagra.

It was designed by Warren Powers Laird & Paul Philippe Cret,[5] who also designed six other buildings on campus: the Central Heating Station, the Stock Pavilion, Lathrop Hall, the Home Economics Buildings, Wisconsin High School, and Sterling Hall.