[3] From 1956 to 1962, DeSoto High School was located at 200 East Belt Line Road.

As the district continued to grow, voters approved a $7.5 million bond by a vote of 445–366 in 1973 that contained a provision for the construction of a new high school.

The building contract was awarded to Central Texas Construction of Terrell at a cost of approximately $3,100,000.

To relieve overcrowding, an adjoining Freshman Campus opened in 1997 to serve the district's ninth graders.

In 2011 The Dallas Morning News reported that the school "had a lower-than-expected college readiness percentage.

[9] In 2016, the boys' team won the 6A State Championship, upsetting #1 ranked Atacostia High 73–54.

[10] In 2016, the Varsity Football team won the 6A Division II State Championship in the AT&T Stadium.

[16] In January 2005, the school district was investigated by the press for its questionable hiring of an outside "gang consultant".