It was there that they discovered their mutual fascination for films and music of the 1960s and 1970s: "very basic cult teenager things, from Easy Rider to the Velvet Underground".

[7] The two and Laurent Brancowitz eventually joined to form an indie rock trio called Darlin', in which Homem-Christo performed guitar.

"[7] A negative review referred to their music as "a daft punky thrash",[8] which inspired Bangalter and Homem-Christo's new name.

Homem-Christo is credited for designing the Daft Punk logo in the liner notes of Homework (1997), the duo's first album.

Regarding Daft Punk's creative process and working with Bangalter, Homem-Christo commented that "he's much more of the tech guy than I am.

[10] Homem-Christo is a co-founder of the group Le Knight Club, along with Éric Chedeville from Pumpking Records.

Following the release of Daft Punk's fourth album Random Access Memories, Homem-Christo and Bangalter collaborated on two tracks with the Weeknd, "Starboy" and "I Feel It Coming", with the former gaining the duo their first number one on the Billboard Hot 100 and the latter, co-written by Chedeville of Le Knight Club, peaking at number four.

[16] Homem-Christo and Bangalter both contributed writing and production credits to the 2017 song "Overnight" by Parcels.

[18] Homem-Christo worked on the title track to Charlotte Gainsbourg's fifth studio album Rest, released in 2017.

[19][20] In 2020, during the COVID-19 pandemic, Homem-Christo created a curated playlist called "Star of a hero" for Italian brand MEDEA, containing tracks from The Beach Boys, the Weeknd, George Duke, and Thundercat, among others.

[22][23] Friend and collaborator Todd Edwards later clarified that Bangalter and Homem-Christo remain active separately.

With regard to working and collaborating with other artists, Homem-Christo sees it as a matter of timing and creativity, rather than fame and opportunity.