De La Salle currently enrolls 1,036 students, and roughly 99% of each graduating class goes on to attend a university or college.

[9] He was named EBAL Pitcher of the Year, a 2018 MaxPreps National All-American, and Cal-Hi Sports All-State Underclass.

[11][12] In his senior season in 2023, Bear batted .404 and was named first team all-state and the Bay Area News Group Player of the Year.

[13] De La Salle High School holds the national record 151-game winning streak spanning from 1992 to 2004.

In 2010, De La Salle defeated Servite, ranked #7 in the nation, 48–8, to win the state title game for a second straight year.

The Lancers, coached by St. Francis alum Greg Calcagno, beat De La Salle in the closing seconds of the game by the score of 31-28.

[18][19] In the minds of the Brothers, their purpose "is to give a human and Christian education to the young, especially the poor, according to the ministry which the Church has entrusted to it."

Students have the opportunity to participate in many retreats and immersion experiences throughout their time at the school, including a "Ven a Ver" program (Come to See), which involves spending five days with the disadvantaged people of Salinas or Tijuana.