De La Salle School, Eccleston, St Helens is an 11-16 mixed comprehensive Roman Catholic high school which is linked to the worldwide La Sallian community.

The school in its current form was created in 1987 after the amalgamation of several Roman Catholic high schools in the area (West Park, Notre Dame, St. Edmund Campion and Mount Carmel).

Twelve years earlier in 1899, Father Hearne, the parish priest of Sacred Heart, had bought a house in St George's Road and set up a Catholic school for boys to complement the school for girls opened by the Sisters of Notre Dame.

It was recognised as a Secondary School and was receiving small grants from the St Helens Education Committee.

The Education Committee subsequently withdrew grants on the grounds of inadequate accommodation and insufficient teaching facilities.