"De Mí Enamórate" was featured as the main theme for Televisa's Mexican telenovela El Camino Secreto (1986-1987), produced by Emilio Larrosa.

On the 2008 recap for the "100 Greatest Songs of the 80's in Spanish" by VH1 Latin America "De Mí Enamórate" ranked at number 74.

[4] The song debuted on the Billboard Hot Latin Tracks chart at number 39 on October 25, 1986, and climbed to the top ten three weeks later.

[12] The writer of the song Juan Gabriel, Myriam, Chon Arauza, Patricia Manterola, Sol Morena, Sergio George and Manoella Torres also recorded their own version of the track.

[13] On the 2008 Juan Gabriel Tribute album Amo al Divo de Júarez, Delux recorded a rock version of the song.