The De la Gardie family (also de la Gardie) is the name of a distinguished Swedish noble family of French origin, whose members held significant political and military positions throughout the history of the Kingdom of Sweden.

[1] The family's social status in France is uncertain; the founder, Ponce d'Escouperie, son of a tradesman, came to Sweden as a mercenary in 1565 and took the name Pontus De la Gardie when registered by the House of Knights.

He was given the title friherre in 1571 and married Sofia Johansdotter Gyllenhielm, an illegitimate daughter of king John III in 1580.

The baronial title ended with his eldest son John De la Gardie.

The current head of the family, Carl Gustaf De la Gardie (1946– ), lives outside Linköping.