[2] In the mid-1980s, Haspiel worked at Upstart Associates (a shared studio space on West 29th Street in New York City)[3] as an assistant for Howard Chaykin on American Flagg!

[4] Haspiel went on to co-create the two-man comics anthology Keyhole with cartoonist Josh Neufeld (a fellow graduate of LaGuardia High School).

Also in 2008, Françoise Mouly's Toon Books published Mo and Jo: Fighting Together Forever, written by Jay Lynch and drawn by Haspiel.

[13][14] In 2011, Haspiel helped spearhead the creation of Trip City, "a Brooklyn-filtered, multimedia, literary arts salon featuring free regular exclusive content created by a fellowship of 21st Century auteurs.

[16] Since 2016, Haspiel has been writing and drawing the serialized webcomic The Red Hook, about a master thief living in the "New Brooklyn Universe," for Webtoon.