Dean and his brother Sam are from Lawrence, Kansas, due to its closeness to Stull Cemetery, a location famous for its urban legends.

Sam joins Dean on the road, hunting various supernatural creatures, tracking down their father and searching for the culprit behind the deaths of their mother and Jessica.

After eventually reuniting with their father and coming into possession of the Colt, they prepare to strike back against Azazel, a powerful demon with yellow eyes.

In a turn of events, Sam is stabbed in the back and killed, forcing Dean to make a deal to save his brother's life.

While trying to cope with his impending death and make the best of his final year, Dean begins to start hunting the freed Demons.

Learning Lilith to have taken the throne of Hell from Azazel and to hold Dean's life contract in her hands, the brothers eventually confront her.

Struggling with his actions in Hell and trying to get Sam to quit drinking demon blood, Dean meets Azazel again when sent back in time by Castiel.

Eventually, Dean learns that the angels the want the Apocalypse to start and that if one of the Demon's Special Children, of whom Sam is the only one left, kill Lilith, Lucifer will be free.

[14] Upon the death of the Archangel Gabriel, the brothers discover that by using the rings from the Four Horsemen of the Apocalypse, they can reopen and trap Lucifer back into Hell.

Getting Sam's soul back, from Lucifer's cage, through Death, the brothers begin to unravel a conspiracy involving Crowley and Castiel.

Defeating Eve, the mother of all monsters, Dean cuts ties with Lisa and learns Castiel to have taken Purgatory's souls to become the most powerful angel alive.

Requesting Death's help, Dean is unable to get Castiel to return the souls of Purgatory in time and the Leviathans break free and begin an effort to take over the Earth.

After their father figure Bobby is killed by Dick Roman, the Leviathan leader, they gain an ally through Kevin Tran, a new prophet.

Dean aids Sam in completing the trials, and along the way they encounter the rogue angel Metatron and the Knight of Hell Abaddon.

Praying for help, Dean learns Metatron fooled Castiel and stole his grace leaving him human and causing the fall.

After eventually growing more and more powerful while losing control, Dean learns from Cain, before killing his ancestor, that there is no viable cure.

Still abandoning his plan to seal himself in the Malik box, Dean accompanies Sam, Castiel, and Jack in a fairly routine hunt.

After slaughtering many hunters in his wake, Michael tortures the Winchesters but is confronted and killed by Jack Kline, who uses his soul to draw on his angelic abilities.

Chuck kills Jack and releases every evil spirit from hell to attack the trio in a dramatic show of frustration, with a prequel statement "Story's over.

After Chuck brings on the end by breaking open the gates of hell, Sam, Dean and Castiel deal with the aftereffects, fighting off a horde of zombies and ghosts.

Narrating these events, Dean Winchester reveals that, unbeknownst to the group, the Akrida are a threat to all of existence and he intends to continue searching for more information on this lost chapter of his parents' lives.

While driving through Heaven after his death, Dean had taken a detour through the multiverse looking for a world where his family got a happy ending, only to find the Akrida who were created by Chuck as a failsafe in case of his defeat.

He then vanishes with Jack and Bobby to return to Heaven, content that he had found a world where his family had a chance at a happy ending as Dean had wanted.

He is also adept at brawling, and knife fighting, and has subdued several human assailants with ease and bested physically more powerful creatures such as shapeshifters, vampires and demons.

Dean also possesses extensive knowledge of the supernatural, and mythology, and from season 4 onwards learns and is able to perform spells that are effective against angels.

Dean's work as a hunter requires him to impersonate various occupational roles in pursuing his investigations and avoid the attention of law-enforcement.

To this end, Dean is well-versed in how police, and various other governmental agencies, such as the FBI and CDC, typically operate and conduct investigations.

In supporting this lifestyle, Dean is also skillful in lock picking, breaking into security systems, carjacking and hustling for pool.

As a human, Dean was the bearer of the Mark of Cain; this granted him extraordinary strength, allowing him to fight on the level of a supercharged angel like Metatron.

His demonic powers also included a degree of telepathy, being able to read an individual named Lester's mind and learn his history with Sam upon meeting him.