Petherbridge's practice was drawing-based (predominantly pen and ink drawings on paper), although she also produced large-scale murals and designed for the theatre.
The Primacy of Drawing: Histories and Theories of Practice was published June 2010 and curated exhibitions included The Quick and the Dead: Artists and Anatomy, 1997, Witches and Wicked Bodies, 2013.
After early years as a painter, producing soft-sculpture and sometimes employing anti-war imagery, Petherbridge turned to monochromatic pen and ink drawing as her primary medium in the 1970s.
[5] These have again become the dominant theme for large multi-panelled drawings, such as The Destruction of the City of Homs, 2016 (Tate, London; on display in Walk Through British Art: 60 Years).
[6] In celebration of drawing as a portable, immediate and expeditious medium, Petherbridge has produced work in other venues than her studio while undertaking drawing residencies at Manchester City Art Gallery, UK(1982) Lalit Kala Akademi Studios Calcutta (British Council sponsored) (1986), Monash University, Melbourne, Australia (2003), Beaconhouse National University, Lahore, Pakistan (2005) and the National Art School, Sydney (2011).
[7][8][9] Petherbridge's teaching career included sessional lectureships at the Architectural Association, London (1981–85), the Fine Art departments of the University of Reading and Middlesex Polytechnic (1984–1987).
Petherbridge began contributing reviews and articles to Architectural Review in 1979 and has written extensively for specialist journals and the daily press including Architects' Journal, Crafts Magazine, Building Design and the Financial Times in the 1980s, when she ran a regular column in Art Monthly commenting on commissioning, sponsorship and the social structures of visual art communities in the United Kingdom.
She has written many catalogue essays and chapters in books and in recent years has published in academic journals on a wide range of contemporary and historical issues in art and architecture, with a particular focus on drawing.